This may be a flavour of the month thing perhaps but Infection Free Zone has just come out. Zombie survival strategy game with a slight twist... You can play in pretty much any place in the world! The developer do the same with the fun 911 operator as well but this has a bit more to it.
It's quite interesting the way that it takes the real world locations and adapts it into use. As an example, with knowledge of town, I set up my headquarters just off the town centre, but from there I was able to correctly pick up some fuel from a local petrol station, raid the supermarkets for food and pick up medical supplies from the doctors surgery... All in the correct places. Downside is getting better weapons, funnily enough English market towns are not particularly equipped for heavy armaments but it's a clever little idea and being able to set up pretty much anywhere gives you a lot for potential run throughs.