Alright. I can't help you too much without knowing what you're running, but I can probably help you more than just saying "adjust the sliders."
You can start by practicing against godawful teams like UTSA and New Mexico State. If you're being carved up by the read option, use QB spy plays and then use another player to play the RB. Also, try and spread the field against the read option. Use the sideline as your 12th player and try to push the play towards the boundary. Finally, and this works for both the run and the read option, use the LB and DL shifts to get an extra step on the offense if you think you can predict where they're going to go.
It should be noted that defense is just a bitch in 14. I generally like to play a base cover 3 and then switch to man coverage on blitz plays, but zone coverage is so soft in NCAA that it's essentially useless.